Prevalence, patterns, and factors associated with bleeding tendencies in dengue.
نویسندگان
چکیده
INTRODUCTION The pattern of bleeding tendencies in dengue and its corellation with platelet count and other factors requires clarification. METHODOLOGY A retrospective study on bleeding tendencies in adults with dengue and platelet counts of less than 100,000 per mm(3) was conducted. Factors associated with bleeding were analyzed. The study cohort were grouped as dengue with severe thrombocytopenia when platelet count was < 50,000/mm(3) and as dengue with moderate thrombocytopenia if platelet count was 50,000-100,000/mm(3) RESULTS: A total of 638 patients formed the study cohort. A 24.1% prevalence of bleeding tendencies was observed. Prior anti-platelet drug intake, platelet count of < 70,000/mm(3), international normalized ratio > 2.0, and partial thromboplastin time > 60 seconds were associated with bleeding. Esophagogastroduodenoscopy was found to identify structural gastroduodenal lesions when dengue was complicated by hematemesis or melena. CONCLUSIONS The results of this study suggest that bleeding complications in dengue can occur at platelet counts of up to 70,000/mm(3), and that prior anti-platelet drug intake increases bleeding risk. Evaluation of hematemesis or melena in dengue with esophagogastroduodenoscopy is beneficial.
منابع مشابه
Risk factors associated with development of dengue haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku Ampuan Afzan Kuantan.
A retrospective study was conducted to investigate 183 serologically-confirmed cases of dengue fever (DF) admitted from October 2004 to March 2005 in a large hospital in Pahang. Clinical and laboratory features, progress and outcome of these patients were analysed in order to identify risk factors associated with development of dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). In...
متن کاملPathological patterns of endometrial curettage samples in women referred with abnormal uterine bleeding: A descriptive study
Introduction: Abnormal uterine bleeding (AUB) is among the most complex gynecological problems, especially during the middle and old age. The aim of this study was to assess the pathological findings in endometrial curettage samples of abnormal uterine bleeding and the risk factors associated with them. Methods: In our cross-sectional study, we included all the referring women with AUB compl...
متن کاملPrevalence and risk factors for low birth weight in Ardabil, Iran.
Introduction Low birth weight (LBW) is the most common cause of neonatal death in developing countries. The objective of our study was to determine the prevalence and risk factors associated with low birth weight in Ardabil, Iranfrom 2010 to 2011.Methods In a case–control study all live newborns were weighted without clothing using a standard calibrated scale. Gestational age was calculated usi...
متن کاملThe prevalence and risk factors of gingivitis in a population of 6-year-old children in Iran
BACKGROUND AND AIM: Gingivitis is a reversible inflammation of gingival tissue. The prevalence of gingivitis is different in various communities. The aim of this study was to determine the prevalence of gingivitis among 6-year-old (± 3 months) children of Rayen, Kerman, Iran.METHODS: In this cross sectional study, 279 children (129 boys and 150 girls) from all Rayen’s nursery schools and primar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of infection in developing countries
دوره 9 1 شماره
صفحات -
تاریخ انتشار 2015